Healthcare case studies
Peptide and Protein Microarrays: New opportunities for studying the interaction of biomolecules
Microarrays are miniaturized analytical devices. On a flat solid substrate of a few cm², such as microscope glass slides or the bottom of a 96-well plate, probe biomolecules are arrayed using a robot. These probes can be peptides, (1) proteins, (2) antibodies or polysaccharides. (3) They are used to capture target biomolecules present in the sample. Target capture is detected by various methods, with Fluorescence being the most widely used. Peptide and protein microarrays offer many applications such as the detection of infections, study of autoimmune diseases, screening of sample banks, simultaneous profiling of proteins, disease markers or the monitoring of immunization as it is the case here.