A Complete multiplex solution for blood grouping
The versatility of SirYus-IH offers an easy transfer to existing lab workstations and could replace gel cards in a near future. The SirYus-IH technology’s breakthrough enables automated, fast and low-cost multiplex blood grouping tests
SirYus-IH is an innovative patented multiplex approach using hemagglutination principles. This method allows the complete blood grouping (ABO, D, IAT and RhKhell) using only 4 wells instead of tens. The process will require few microliters of samples with a time to result equivalent to gel cards.
The SirYus-IH products consist of:
Test wells printed with anti-group antibodies for the in-parallel capture of red blood cells
- Reagents required for RBC dilutions and handling
- Tests are designed to run on gel cards workstations and enable to multiplex existing tests when using same reagents and consumables.
Key points of SirYus-IH
- Easy to implement: same process as gel cards
- Cost reduction: test wells, reagents and wastes are rationalized,
- Workflow improvement
The way it works
Comparison chart
GEL CARD BASED ASSAY | ![]() |
ALTERNATIVE MULTIPLEXE APPROCHES | |
Sample needed | 5 µL of red cell or 50 µL of plasma | <5 µL of red cell or <100 µL of plasma |
3 µL of red cell or 80 µL of plasma |
Buffer | LISS based buffer | Existing commercial buffer | Nd |
Time to first result | < 10 min for direct and back typing, IAT or phenotyping | < 10 min for direct and back typing or phenotyping, 30min for IAT | 35 min |
Throughput | < 1000 samples/h | High versatility and easy adaptation on existing systems | >2000 samples/h |
DEVICE | |||
Format | 6-8 Simplex tests | 8 Multiplex tests | 2 Multiplex tests cartridge |
Material | Plastic | Plastic | Glass slide (Safety issue) |
Shelf life | > 6 months | 6 months | |
Waste, reagents and consumables | One set per plex | 5 times less, average | 5 times less average |
COGS | Due to concept, SirYus is highly competitive |